PRECLINICAL & TRANSLATIONAL
RESEARCH
Genemarkers provides preclinical and translational research services to generate high-quality, reliable genomic and proteomic data from in vitro models and clinical samples. For over 15 years, Genemarkers has been a trusted partner, supporting IND submissions and planning for early-stage clinical trials across therapeutic indications.
Cell & Tissue Models
Genemarkers offers cell and tissue models to support preclinical and translational research. Our expertise and advanced cell culture capabilities provide robust tools and methods to strengthen drug discovery, development, and safety testing.
Cell & Tissue-Based in vitro models
- Skin & Dermal Disease Models
- Neuronal Models
- PBMCs
- Intestinal, Ocular, Vaginal, Nasal, and More
Dermal Tissue Models
- 2D Monolayer & Coculture
- 3D In Vitro Tissue Models
- Ex Vivo Skin Models
- AD/Psoriasis Disease Models
Tissue Challenges
- UVA and UVB Irradiation
- Blue Light (HEV)
- Diesel Particulate Matter (DPM) & Diesel Engine Exhaust (DEE)
- Skin Wounding & Inflammatory Responses
Genomic Biomarker Analysis
Genomic biomarker analysis plays a crucial role in preclinical and translational research, helping to identify mechanisms of action, discover novel biomarkers, determine dose-response relationships, and validate safety and efficacy.
Genomic Biomarker Analysis Services:
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- CYP450 Genotyping
- Whole Exome Sequencing (WES)
- mRNA-Seq (Illumina)
- TaqMan qPCR (mRNA & microRNA)
PROTEIN Biomarker Analysis
Protein biomarker analysis helps you validate biological targets, monitor and understand pharmacokinetic and pharmacodynamic effects, and assesses safety and efficacy in preclinical and translational studies.
Protein Biomarker Analysis Services:
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- Protein Expression (MSD, ELISA)
- Immunohistochemistry
- Method Development & Validation
Sample Management
Genemarkers understands the critical nature of managing precious clinical samples. From clinical sample collection, shipping, and storage, our IATA-certified team will collaborate directly with your clinical sites to offer end-to-end sample management solutions, ensuring your valuable clinical samples are properly handled at every step of the process.
Sample Preparation
- DNA/RNA, Protein Isolation from In Vitro, Animal & Non-mammalian Cells & Tissues
- Manual & Automated Protocols
- Quantity/Quality Analysis of DNA/RNA (NanoDrop, BioAnalyzer, Qubit)
- Method Transfer & Assay Validation
Sample Collection Kitting
- Standard & Custom Sample Collection Kits
- Dedicated, IATA-Certified Client Services/Logistics Team
- Whole Blood, Serum, Plasma, Tissue Biopsies, Tape Strips, Skin Swabs, etc
- Global Kit Distribution & Inventory Management
- Short & Long-Term Sample Storage
Computational Data Analysis
- Statistical Analysis
- Pathway Analysis
- Data Interpretation
Our Process
At Genemarkers, we partner closely with your team, acting as an extension of your scientific staff to ensure every study is executed with precision and efficiency. Our approach integrates seamlessly into your workflow, delivering high-quality data with rapid turnaround. Our team will help to manage all aspects of sample collection kitting, distribution of kits to global clinical sites, and instructions for storage/shipment specific to each sample type. With proactive communication, real-time tracking, and personalized support, we help you maintain study organization, adherence to timelines, and sample quality, so you can focus on advancing your research goals.
Contact the GENEMARKERS Team
Have questions? Interested in learning more about how Genemarkers can help? Fill out the form below and a member of our team will reach out shortly.