BIOPHARMA SOLUTIONS
At Genemarkers, we understand the importance of generating high quality data in a time and cost efficient manner. As a contract research organization (CRO) with more than 15 years of experience, we offer genomic and proteomic biomarker testing to support all phases of drug development – from preclinical & translational through clinical trials, with specific expertise in dermatology, inflammatory conditions and neuroscience.
Preclinical & Translational Testing Services
Sample Collection Kitting
- Standard & Custom Sample Collection Kits
- Dedicated Client Services/Logistics Team
- Whole Blood, Serum, Biopsies, Tape Strips, etc.
- Global Kit Distribution/Inventory Management
Cell & Tissue-Based In Vitro Models
- Skin & Dermal Disease Models
- Neuronal Models
- PBMCs
- Intestinal, Ocular & Other
Sample Preparation
- DNA/RNA, Protein Isolation from in vitro, animal & non-mammalian cells & tissues
- Manual & Automated Protocols
- Quantity/Quality QC of DNA/RNA (NanoDrop, BioAnalyzer, Qubit)
Genomic Biomarker Analysis
- CYP450 Genotyping
- Whole Exome Sequencing (WES)
- mRNA-Seq (Illumina)
- Taqman qPCR (mRNA, microRNA)
- Microbiome Testing
- Assay Validation
Protein Biomarker Analysis
- Protein Expression (MSD, ELISA)
- Immunohistochemistry
- Method Development & Validation
Computational Data Analysis
- Statistical Analysis
- Data Interpretation
- Pathway Analysis
At Genemarkers, we accelerate your clinical trials with cutting-edge genomic and proteomic biomarker testing services, backed by our CAP and CLIA-certified laboratory. Whether you’re in the early or late stages of your trial, we deliver precise, timely results with unwavering commitment to data accuracy and sample integrity.
We understand the critical nature of your timelines and are dedicated to helping you achieve success every step of the way.
Biomarker Testing Services
- Nucleic Acid Isolation (DNA, RNA)
- Targeted qPCR
- RNA Sequencing (Illumina)
- Whole Exome Sequencing
- ELISA
- Multiplex Proteomic Panels (MSD, ELISA)
- Histology & Immunohistochemistry
- Assay Development & Validation
- Bioinformatics & Data Analysis
Kitting & Sample Logistics
- Collection Kitting Expertise (Biopsies, Tape Strips, Blood, Serum, Plasma, Buccal Swabs, etc.)
- Customizable E-Manifests & Barcoding
- Full-Time IATA Certified Logistics Team; On-call Customer Service
- Global, Multi-Site Distribution
- Short-Term and Long-Term Sample Storage
IMPROVE PATIENT RECRUITMENT with Pharmacogenomic (PGX) Testing
Elevate the safety and success of your clinical trials with pharmacogenomic insights. Genotyping empowers your team to identify patients at higher risk for adverse events and tailor drug dosages to specific subpopulations, ensuring precision and safety.
Your Clinical Trial
Therapeutic Expertise In Dermatology
Genemarkers is a leader in dermal drug development, bringing unparalleled expertise in working with in vitro and ex vivo dermal cells, tissues, and clinical samples including skin biopsies and tape strips. Our extensive experience drives the success of your projects, ensuring precise, reliable results that accelerate your development process.
|In Vitro| Dermal Models
- 2D monolayer & coculture (Keratinocytes, Fibroblasts, Melanocytes, Adipocytes, Dermal Papilla Cells, Sebocytes, PBMCs)
- 3D In Vitro Tissue Models
- Ex Vivo Skin Models
- Ex Vivo Wounded Tissue Models
- Ex Vivo AD/Psoriasis Disease Models
|In Vitro| Tissue Challenges
- UV Irradiation
- Blue Light (HEV)
- Diesel Particulate Matter (DPM) & Diesel Engine Exhaust (DEE)
- Skin Wounding Methods
- Inflammatory Responses
Analysis from Clinical Samples
- Skin Biopsies
- Tape Strips
- Scalp Tissue
- Hair Follicles
- Blood, Serum, PBMCs
Genemarkers provides off-the-shelf solutions for evaluating biomarkers to expedite drug discovery and development across a wide range of therapeutic conditions. Our expertise includes utilizing neural and inflammatory cell lines and models.
Inflammation Services
- In vitro cell culture of PBMCs, macrophages and other immune cells
- Gene and protein expression cytokine/chemokine panels
- Analysis from human clinical serum/plasma/blood samples
- Comprehensive list of validated ELISAs
- Method development and validation
CNS Services
- In vitro cell culture of neuronal and glial cells
- Development of complex in vitro models
- Targeted neurotransmitter pathway gene expression panels
- Neuroinflammation protein expression panels
Contact the GENEMARKERS Team
Have questions? Interested in learning more about how Genemarkers can help? Fill out the form below and a member of our team will reach out shortly.