Genemarkers has developed ex vivo tissue models that mimic key components of atopic dermatitis (AD) and psoriasis to facilitate research of topical compounds for preclinical and clinical drug development. Our scientific team has verified the expression of over 30 AD-specific and 400 psoriasis-specific gene expression biomarkers in the tissue models.
Our stimulated ex vivo tissue models are ideal for performing studies investigating the efficacy of therapeutic compounds. Study endpoints may include: RNA sequencing to assess global changes in gene expression, targeted qPCR, ELISA methods for protein expression analysis, and immunohistochemistry.
Key Features:
- Biomarkers are supported by peer-reviewed, published literature
- Flexible study design options & reproducible results
- Ideal for screening compounds and determining efficacy